Postdoctoral Fellow - Cancer Biology and Epigenetics

City of Hope

Monrovia, CA

Job posting number: #7258566 (Ref:10026851)

Posted: June 27, 2024

Application Deadline: Open Until Filled

Job Description

Thank you for your interest. Please note, the purpose of this posting is to recruit for on-going and future positions.

  • For consideration, please email Dr. Jianjun Chen at [email protected] a single PDF that includes your CV, a brief motivation statement, and contact information of three scientific mentors (references).
  • Pay Rate: $34.00-$37.54 per hour

Join the forefront of groundbreaking research at theBeckman Research Institute of City of Hope, where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. Our dedicated and compassionate faculty and staff are driven by a common mission: Contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting-edge research.

The laboratory of Dr. Jianjun Chen is in search of a talented postdoctoral fellow. Our group is interested in discovering novel genetic and epigenetic regulations and deciphering their underlying molecular mechanisms in normal developmental processes and tumorigenesis. We cover research areas with relevance to Cancer Biology, Cancer Epigenetics, Epigenetics Regulation, Cancer Metabolism, Immunology, Drug Discovery, Development, and Structural Biology, with an emphasis on RNA epigenetics (RNA modifications) and DNA epigenetics (mainly focusing on the TET1/2/3-mediated DNA demethylation) associated basic and translational research. Our research involves experiments with primary human cancer cells, cancer and stem cell transplantation models, mouse genetics, molecular biology, biochemistry and cell biology, chemical biology, immunology, functional genomics, signal transduction, single-cell sequencing, spatial sequencing, metabolism, drug development, structural biology, and large-scale data analysis and computational biology.

For more information about Dr. Chen’s lab, please visit here.

As a successful candidate, you will:

Engage in a variety of advanced techniques, including but not limited to flow cytometry, mass spectrometry/quantitative phospho-profiling, CyTOF, mouse genetic models, xenograft assays, retroviral gene delivery, chemical biology, drug development, whole exome sequencing and RNA-seq analysis of clonal evolution of cancer, dot blots, RNA modification-seq, ChIP-seq, RIP-seq, PAR-CLIP-seq, and pre-clinical drug testing in xenotransplantation models.

Your qualifications should include:

  • Ph.D. and/or M.D. degree(s), and a solid background in biochemistry, chemical biology, mouse model studies, development, epigenetics, immunology, pathology, metabolism, structural biology, drug discovery, and/or stem cell research.
  • The candidates should be highly motivated individuals with the ability to work in a team environment and with good oral and written communication skills in English.

City of Hope is an equal opportunity employer. To learn more about our commitment to diversity, equity and inclusion, please click here.

To learn more about our Comprehensive Benefits, pleaseCLICK HERE.


The estimated pay scale represents the typical [salary/hourly] range City of Hope reasonably expects to pay for this position, with offers determined based on several factors which may include, but not be limited to, the candidate’s experience, expertise, skills, education, job scope, training, internal equity, geography/market, etc. This pay scale is subject to change from time to time.

City of Hope is a community of people characterized by our diversity of thought, background and approach, but tied together by our commitment to care for and cure those with cancer and other life-threatening diseases. The innovation that our diversity produces in the areas of research, treatment, philanthropy and education has made us national leaders in this fight. Our unique and diverse workforce provides us the ability to understand our patients' needs, deliver compassionate care and continue the quest for a cure for life-threatening diseases. At City of Hope, diversity and inclusion is a core value at the heart of our mission. We strive to create an inclusive workplace environment that engages all of our employees and provides them with opportunities to develop and grow, both personally and professionally. Each day brings an opportunity to strengthen our work, leverage our different perspectives and improve our patients’ experiences by learning from others. Diversity and inclusion is about much more than policies and campaigns. It is an integral part of who we are as an institution, how we operate and how we see our future.

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Job posting number:#7258566 (Ref:10026851)
Application Deadline:Open Until Filled
Employer Location:City of Hope
United States
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