Postdoctoral Fellow - Tumor-Colonizing Bacterial Immunotherapy

City of Hope

Duarte, CA

Job posting number: #7221272 (Ref:10024705)

Posted: February 27, 2024

Salary / Pay Rate: $34.00 - $37.55 / hour

Application Deadline: Open Until Filled

Job Description

Join the forefront of groundbreaking research at the Beckman Research Institute of City of Hope, where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. Our dedicated and compassionate faculty and staff are driven by a common mission: Contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting-edge research.

A Postdoctoral Fellow position is available in the laboratory of Edwin R. Manuel, Ph.D., at City of Hope, Beckman Research Center, Monrovia, CA. Our lab is interested in utilizing tumor-colonizing, bacterial-based agents as novel immunotherapy for solid and hematologic malignancies. We are recruiting enthusiastic, motivated scientists who are seeking a fast-paced academic research environment. Our lab in the Department of Immuno-Oncology focuses on engineering tumor-colonizing bacteria to target components of the tumor microenvironment that contribute to poor drug delivery, immune suppression, and cancer metabolism. For more information about Dr. Manuel’s lab, please visit here.

As a successful candidate, you will:

  • Have the opportunity to learn and to develop research publications and presentations, independent grant applications, and independent projects that they can take with them when they leave the lab Design, perform and lead projects involving optimization of bacterial-based agents designed to elicit tumor-specific immunity, enhance drug delivery, and suppress cancer metabolism.
  • Coordinate lab tasks and operations among multiple lab members, including ordering, inventory, and other essential lab functions.
  • Prepare laboratory reagents, chemicals, instruments, and maintain equipment.
  • Keep detailed and accurate logs of experiments from conception to analysis, as well as of lab inventory and mouse colonies.
  • Record data meticulously and analyze and synthesize results using industry standard application suites.
  • Help to prepare presentations and manuscripts for publication.
  • Initiate and maintain collaborations with other labs.
  • Travel to meetings to represent the lab and to present new data.

Your qualifications should include:

  • Ph.D. in immunology or related field.
  • Expertise with flow cytometry, immunologic assays, cell culture, basic microbiology and molecular biology techniques is ideal.
  • Experience with high-resolution imaging platforms and mass cytometry (CyTOF) or mass spectrometry is a plus.
  • Ideal candidates will be highly motivated and have ambitions to further develop scientific and career skills. They will have a desire to be challenged and to learn new scientific strategies and techniques.

City of Hope is an equal opportunity employer. To learn more about our commitment to diversity, equity and inclusion, please click here.

Salary / Pay Rate Information:
Pay Rate: $34.00 - $37.55 / hour

The estimated pay scale represents the typical [salary/hourly] range City of Hope reasonably expects to pay for this position, with offers determined based on several factors which may include, but not be limited to, the candidate’s experience, expertise, skills, education, job scope, training, internal equity, geography/market, etc. This pay scale is subject to change from time to time.



City of Hope is a community of people characterized by our diversity of thought, background and approach, but tied together by our commitment to care for and cure those with cancer and other life-threatening diseases. The innovation that our diversity produces in the areas of research, treatment, philanthropy and education has made us national leaders in this fight. Our unique and diverse workforce provides us the ability to understand our patients' needs, deliver compassionate care and continue the quest for a cure for life-threatening diseases. At City of Hope, diversity and inclusion is a core value at the heart of our mission. We strive to create an inclusive workplace environment that engages all of our employees and provides them with opportunities to develop and grow, both personally and professionally. Each day brings an opportunity to strengthen our work, leverage our different perspectives and improve our patients’ experiences by learning from others. Diversity and inclusion is about much more than policies and campaigns. It is an integral part of who we are as an institution, how we operate and how we see our future.


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