TGen Postdoctoral Fellow - Single-Cell Proteomics - Arizona

City of Hope

Phoenix, AZ

Job posting number: #7206492 (Ref:10024425)

Posted: January 12, 2024

Application Deadline: Open Until Filled

Job Description

JOIN US MARCH 5th! You’re invited to a live virtual presentation featuring Ajay Goel, Ph.D., AGAF hosted by City of Hope to share insights on his research and provide valuable information to candidates for his programs during this 20-minute live presentation! Stay for the Q & A session immediately following. We begin at 2 pm and you must register to join: Bring your resume’, your questions and a friend! *All are welcome.

More about Dr Goel here: Ajay Goel, Ph.D., AGAF, Chair, Department of Molecular Diagnostics and Experimental Therapeutics | Beckman Research Institute of City of Hope

About TGen

TGen, the Translational Genomics Research Institute, is an affiliate of City of Hope. We are an Arizona-based, nonprofit medical research institute dedicated to conducting groundbreaking research with life-changing results. We work to unravel the genetic components of common and complex diseases, including cancer, neurological disorders, infectious disease, and rare childhood disorders. By identifying treatment options in this manner, we believe medicine becomes more rational, more precise and, well, more personal.

We are focused on translational science – and have been since our formation in 2002. Our immediate goal is to make a difference in the lives of patients suffering from disease. We are moderately sized (~300 employees), nimble, and house the latest technologies in genomics. Do you dream of your work benefiting patients sooner rather than later? We have a 20-year track record in doing exactly that. It is the perfect sized place for you to start and grow your career and receive expert mentorship from a diverse, successful group of investigators.

Position Summary

The Pirrotte lab is actively seeking a highly motivated and skilled individual to join our dynamic team as a Post-Doctoral Fellow. This position offers a unique opportunity to contribute to the forefront of scientific discovery by developing innovative methods in single-cell proteomics and applying them to translational cancer research. You will have access to state-of-the-art mass spectrometry instrumentation in Pirrotte Lab including Bruker timsTOF Ultra, timsTOF HT, Orbitrap Eclipse, Orbitrap Fusion Lumos and TSQ Altis mass spectrometers. The Pirrotte lab is also equipped with a CELLENION cellenONE single-cell isolation and sample preparation platform, and various automation systems.

You must possess a strong background in mass spectrometry, cell biology, proteomics sample preparation, and advanced quantitative data analysis, with a particular emphasis on interpreting complex results.

Key Responsibilities:

· Develop and optimize methods for single-cell proteomics.

· Apply cutting-edge techniques to advance translational research objectives.

· Conduct proteomics sample preparation and mass spectrometry experiments.

· Perform data analysis and interpretation of results.

· Collaborate with multidisciplinary teams to integrate bioinformatics approaches.

· Disseminate results at conference meetings and author manuscripts.

If you are passionate about pushing the boundaries of single-cell proteomics, contributing to translational research, and working in a collaborative and innovative environment, we encourage you to apply. Please include a CV, a personal statement, and at least three references that can be contacted.


· PhD in a relevant field (e.g., biochemistry, molecular biology, or a related discipline).

· Proven experience in mass spectrometry, cell biology, and proteomics.

· Bioinformatics expertise is a plus.

· Experienced in conducting research, publishing journal manuscripts, presenting research at conferences, and advanced quantitative data analyses.

To Apply please click the link below:

The estimated pay scale represents the typical [salary/hourly] range City of Hope reasonably expects to pay for this position, with offers determined based on several factors which may include, but not be limited to, the candidate’s experience, expertise, skills, education, job scope, training, internal equity, geography/market, etc. This pay scale is subject to change from time to time.

City of Hope is a community of people characterized by our diversity of thought, background and approach, but tied together by our commitment to care for and cure those with cancer and other life-threatening diseases. The innovation that our diversity produces in the areas of research, treatment, philanthropy and education has made us national leaders in this fight. Our unique and diverse workforce provides us the ability to understand our patients' needs, deliver compassionate care and continue the quest for a cure for life-threatening diseases. At City of Hope, diversity and inclusion is a core value at the heart of our mission. We strive to create an inclusive workplace environment that engages all of our employees and provides them with opportunities to develop and grow, both personally and professionally. Each day brings an opportunity to strengthen our work, leverage our different perspectives and improve our patients’ experiences by learning from others. Diversity and inclusion is about much more than policies and campaigns. It is an integral part of who we are as an institution, how we operate and how we see our future.

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