Postdoctoral Fellow – Cancer Metabolism
Job posting number: #7186199 (Ref:hlj_49993)
Posted: October 13, 2023
Application Deadline: Open Until Filled
Moffitt Cancer Center and Research Institute is proud to be Florida’s only National Cancer Institute-designated Comprehensive Cancer Center located in Tampa. We strive to be the leader in understanding the complexity of cancer through team science and applying those insights for human benefits. Every Team Member of Moffitt focuses on our lasting commitment to our mission: To contribute to the prevention and cure of cancer.
Postdoctoral Fellow – Cancer Metabolism
Research in the Ward Lab is centered on characterizing how systemic metabolism and nutritional status are transmitted to tumor cells via the microenvironment and how mitochondria integrate these metabolic signals during tumor progression and in response to therapy. Current projects in the lab are focused on how substrate availability influences iron-sulfur cluster biosynthesis (bioRxiv 2022.10.06.511221), a process critical to maintaining nearly all aspects of cellular function, and how the mitochondrial transhydrogenase (NNT) exerts its’ pleiotropic regulation of redox metabolism (PMID: 32196080). We are recruiting a postdoctoral fellow eager to explore these topics and other aspects of mitochondrial redox metabolism through the implementation of chemoproteomics, metabolomics, and super-resolution microscopy.
- Use of cutting-edge technologies (e.g. in vivo stable isotope tracing, cysteine-based chemoproteomics, and stimulated emission depletion [STED] super-resolution microscopy).
- Work as part of the Lung Cancer Center of Excellence, which bridges basic and clinical research.
- Work closely with Dr. Ward on the postdoctoral fellow’s career development (e.g., grant/manuscript writing, scientific presentations, and networking).
- Moffitt integrates excellent patient care with cutting-edge clinical and basic research. Having a cancer hospital on-site provides unique opportunities for translational research.
- Outstanding mentorship from expert faculty with wide-ranging funded research programs including T32 Training Grants.
The Ideal Candidate:
- Candidates with research experience in metabolism and/or mitochondrial biology are highly encouraged to apply.
- Practical experience with mass spectroscopy-based proteomics or metabolomics is highly desirable, but not required.
- Experience with mouse models of cancer is also highly desirable, but not required.
- Can think independently and has a strong desire to develop independent projects.
- Has excellent communication skills and the ability to work collaboratively as part of a team.
- Work independently and collaboratively for the mission of the lab.
- Design and execute experiments; analyze and interpret data
- Regularly present findings to the lab and at Moffitt-sponsored seminar series and symposia.
- Attend conferences to present findings to the broader scientific community.
- Mentor and train graduate and undergraduate students.
- Write manuscripts, postdoctoral fellowships, and assist with other funding applications.
Credentials and Qualifications:
- Ph.D. or M.D./Ph.D. in biology, biochemistry, biophysics, molecular biology, or a related field is required. Ph.D. candidates nearing the completion of their degree in relevant fields are encouraged to apply.
- At least one first-author publication or preprint is highly preferred.
Moffitt Postdocs are provided with Medical (Moffitt covers premium for team members) effective upon start date and eligible for Dental, Vision, Paid Time Off, Retirement, Parental Leave and more. You may be eligible for relocation assistance per policy. Reasons to relocate, aside from the sunshine, beaches and year-round outdoor recreation associated with the Gulf Coast of Florida, Tampa is a thriving metropolitan city, which has become a hub for ground-breaking research, welcoming individuals from around the globe. This diverse city is engulfed with rich culture, year-round activities for all, beautiful beaches, amazing cuisine and so much more. We strive for work/life balance.
If you have the vision, passion, and dedication to contribute to our mission,
then we have a place for you.
How to Apply: Interested applicants should send a single PDF file that includes (1) a cover letter summarizing their research training and accomplishments, scientific interests, and career goals, (2) a current CV, and (3) contact information for three references to Dr. Nate Ward at [email protected]
Mission To create a Moﬃtt culture of diversity, equity, and inclusion as we strive to contribute to the prevention and cure of cancer. Vision To advance and accelerate a culture of access, equity, and inclusion. Diversity is a priority at Moffitt and is meant "to promote a culture of diversity and inclusion as we contribute to the prevention and cure of cancer." The Enterprise Equity Department focuses its efforts on eliminating those obstacles to an individual’s ability to exist within their personal comfort zone at the cancer center. Everyone is important to meeting this priority. Addressing and responding to diversity and inclusion fosters an environment where mutual respect for diverse cultures, communication styles, languages, customs, beliefs, values, traditions, experiences and other ways in which we identify ourselves, is the expectation.