Postdoctoral Fellow PhD- Development and Disease

Baylor College of Medicine

Houston, TX

Job posting number: #7162348 (Ref:16888-en_US)

Posted: August 18, 2023

Application Deadline: Open Until Filled

Job Description


The Tom Cooper lab at Baylor College of Medicine has open projects that investigate that investigate two related areas: (1) the mechanisms and physiological consequences of conserved alternative splicing transitions regulated during mammalian postnatal development and (2) the disruption of this regulatory network that is the pathogenic mechanism of the microsatellite expansion disease myotonic dystrophy type 1 (DM1) that affects multiple tissues and is the most common cause of muscular dystrophy in adults. In DM1, the RNA expressed from the expanded allele disrupts regulation of a network of alternative splicing transitions that normally drive fetal to adult protein isoform expression. Expression of fetal protein isoforms unable to perform the functions required in adult tissue causes disease features. The investigations in these two areas are complementary and provide the basis for an exchange of ideas and collaboration within the lab.

Job Duties

  • Plans, directs and conducts research experiments related to gynecological pathologies.
  • Collects, analyzes, and documents experiment results.
  • Performs different cell and molecular biology studies using mice and immortalized cells.
  • Documents results of experiments and reports to principal investigator.
  • Conducts literature searches and summarize information for ongoing projects.
  • Works with others in the lab and other groups as part of collaborations.
  • Maintains mouse colonies.
  • Performs molecular biology and cell biology experiments.

Minimum Qualifications

  • Ph.D. in Basic Science, Health Science, or a related field.
  • No experience required.


Baylor College of Medicine requires employees to be fully vaccinated -subject to approved exemptions-against vaccine-preventable diseases including, but not limited to, COVID-19 and influenza.


Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.





Baylor College of Medicine fosters diversity among its students, trainees, faculty and staff as a prerequisite to accomplishing our institutional mission, and setting standards for excellence in training healthcare providers and biomedical scientists, promoting scientific innovation, and providing patient-centered care. - Diversity, respect, and inclusiveness create an environment that is conducive to academic excellence, and strengthens our institution by increasing talent, encouraging creativity, and ensuring a broader perspective. - Diversity helps position Baylor to reduce disparities in health and healthcare access and to better address the needs of the community we serve. - Baylor is committed to recruiting and retaining outstanding students, trainees, faculty and staff from diverse backgrounds by providing a welcoming, supportive learning environment for all members of the Baylor community.

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Job posting number:#7162348 (Ref:16888-en_US)
Application Deadline:Open Until Filled
Employer Location:Baylor College of Medicine
United States
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