Postdoctoral Associate

Baylor College of Medicine

Houston, TX

Job posting number: #7161097 (Ref:16735-en_US)

Posted: August 4, 2023

Application Deadline: Open Until Filled

Job Description


The St-Pierre lab (; Twitter: @StPierreLab) develops and applies new tools for monitoring and interrogating brain activity with millisecond-timescale temporal resolution. We seek an energetic team member to lead our efforts to characterize and apply new light-responsive proteins in vitro and in vivo. The successful candidate would work on two types of tools: (1) genetically encoded voltage indicators (GEVIs), fluorescent biosensors that report voltage as changes in brightness, and (2) optogenetic silencers, light-gated channels that inhibit neuronal firing. Characterization of these tools requires simultaneous electrophysiological recordings and optical excitation/imaging. This position provides exciting opportunities to work with the latest optical technologies and develop new skills in two-photon voltage imaging, protein engineering, and synthetic biology.

Job Duties

  • Documents results of experiments and reports to the principal investigator.
  • Supervises, schedules and coordinates the activities of less experienced research staff.
  • Cultures mammalian cells.
  • Prepares brain slices, dissociated neurons, or both.
  • Conducts experiments that combine electrophysiology and either optogenetic activation or optical imaging (multi-photon fluorescence microscopy).
  • Maintains an electrophysiological rig, and troubleshooting if needed.
  • Analyzes data using commercial software or customized data pipelines.
  • Teaches techniques, procedures, and experimental design to other members of the lab.
  • Communicates research results in group meetings, national or international conferences.

Minimum Qualifications

  • MD or Ph.D. in Basic Science, Health Science, or a related field.
  • No experience required.

Preferred Qualifications

  • Strong track of publications.


Baylor College of Medicine requires employees to be fully vaccinated -subject to approved exemptions-against vaccine-preventable diseases including, but not limited to, COVID-19 and influenza.


Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.




Baylor College of Medicine fosters diversity among its students, trainees, faculty and staff as a prerequisite to accomplishing our institutional mission, and setting standards for excellence in training healthcare providers and biomedical scientists, promoting scientific innovation, and providing patient-centered care. - Diversity, respect, and inclusiveness create an environment that is conducive to academic excellence, and strengthens our institution by increasing talent, encouraging creativity, and ensuring a broader perspective. - Diversity helps position Baylor to reduce disparities in health and healthcare access and to better address the needs of the community we serve. - Baylor is committed to recruiting and retaining outstanding students, trainees, faculty and staff from diverse backgrounds by providing a welcoming, supportive learning environment for all members of the Baylor community.

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Job posting number:#7161097 (Ref:16735-en_US)
Application Deadline:Open Until Filled
Employer Location:Baylor College of Medicine
United States
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