Postdoctoral Fellow - Diabetes and Cancer Risk

City of Hope

Duarte, CA

Job posting number: #7159210 (Ref:10022339)

Posted: July 18, 2023

Application Deadline: Open Until Filled

Job Description

Thank you for your interest. Please note, the purpose of this posting is to recruit for on-going and future positions.

About City of Hope

City of Hope is an independent research and treatment center for diabetes, cancer and other life-threatening diseases. Bringing together the best in bench-to bedside research, City of Hope’s Arthur Riggs Diabetes & Metabolism Research Institute (AR-DMRI) is one of the world’s most comprehensive diabetes research programs.

City of Hope has a long and impressive history of groundbreaking discoveries in the field of diabetes spanning more than five decades since Rachmiel Levine, M.D., who discovered the role of insulin in glucose transport, launched diabetes research at City of Hope in the 1970s. The Institute is named for Arthur D. Riggs, Ph.D., another pioneer in the field famous for his work on synthesizing the first man-made gene and using synthetic genes to produce human insulin, now the standard of care for people with diabetes worldwide. The AR-DMRI is headed by Debbie Thurmond, Ph.D., a renowned research scientist, professor and founding chair of the Department of Molecular & Cellular Endocrinology.

City of Hope is also home to seminal National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) programs, such as the Human Islet Research Network (HIRN) and the Integrated Islet Distribution Program (IIDP), that lead the field of diabetes in diabetes research and translational potential.

City of Hope is located in Los Angeles, California, with community clinics throughout Southern California. It recently acquired Cancer Treatment Centers of America, extending its national reach. One of only 53 NCI-designated comprehensive cancer centers in the nation, it has been ranked as one of "America's Best Hospitals" in cancer by U.S. News & World Report for over 15 years. Founded in 1913, City of Hope is a pioneer in the fields of immunotherapy and clinical islet cell transplantation for diabetes, bone marrow transplantation and numerous breakthrough cancer drugs, many based on technology developed at the institution.

City of Hope’s commitment to Diversity, Equity and Inclusion

We believe diversity, equity and inclusion is key in serving our mission to provide compassionate patient care, drive innovative discovery, and advance vital education focused on eliminating cancer and diabetes in all of our communities. Our commitment to Diversity, Equity and Inclusion ensures we bring the full range of skills, perspectives, cultural backgrounds and experiences to our work -- and that our teams align with the people we serve in order to build trust and understanding. We are dedicated to fostering a community that embraces diversity - in ideas, backgrounds and perspectives; this is reflected in our work and represented in our people.

Position Summary

The Beckman Research Institute of City of Hope is looking for a talented Postdoctoral Fellow to study the molecular mechanisms involved in the increased risk of cancer in patients with diabetes. The Shuck lab specializes in detailed studies of the cellular impact of reactive molecules produced during metabolic dysfunction. Specifically, we are interested in investigating the induction of covalent adducts on DNA, RNA, and protein using human prostate cancer cell lines. The position will encompass a variety of techniques including sterile cell culture, characterization of cellular changes induced by hyperglycemia, use of biochemical assays, and analytical techniques such as HPLC and mass spectrometry. The trainee will benefit from a close interaction with world-class clinical and basic science faculty and staff, and gain experience in state-of-the-art genomics and analytical techniques.

Basic education, experience and skills required for consideration:

· A Ph.D. degree in life or biomedical sciences, or a related discipline is required.

Additional Information:

· Pay Rate: $31.00 – 34.23 per hour

· The estimated pay scale represents the typical [salary/hourly] range City of Hope reasonably expects to pay for this position, with offers determined based on several factors which may include, but not be limited to, the candidate’s experience, expertise, skills, education, job scope, training, internal equity, geography/market, etc. This pay scale is subject to change from time to time.

· As a condition of employment, City of Hope requires staff to comply with all state and federal vaccination mandates.

· For more information about Dr. Sarah Shuck’s research, please click https://www.cityofhope.org/research/riggs-institute/diabetes-and-cancer-metabolism/shuck-lab

· To apply to the position, please send your resume/cv to [email protected].

City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.

The estimated pay scale represents the typical [salary/hourly] range City of Hope reasonably expects to pay for this position, with offers determined based on several factors which may include, but not be limited to, the candidate’s experience, expertise, skills, education, job scope, training, internal equity, geography/market, etc. This pay scale is subject to change from time to time.



City of Hope is a community of people characterized by our diversity of thought, background and approach, but tied together by our commitment to care for and cure those with cancer and other life-threatening diseases. The innovation that our diversity produces in the areas of research, treatment, philanthropy and education has made us national leaders in this fight. Our unique and diverse workforce provides us the ability to understand our patients' needs, deliver compassionate care and continue the quest for a cure for life-threatening diseases. At City of Hope, diversity and inclusion is a core value at the heart of our mission. We strive to create an inclusive workplace environment that engages all of our employees and provides them with opportunities to develop and grow, both personally and professionally. Each day brings an opportunity to strengthen our work, leverage our different perspectives and improve our patients’ experiences by learning from others. Diversity and inclusion is about much more than policies and campaigns. It is an integral part of who we are as an institution, how we operate and how we see our future.


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Job posting number:#7159210 (Ref:10022339)
Application Deadline:Open Until Filled
Employer Location:City of Hope
Duarte,California
United States
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