H. Lee Moffitt Cancer Center

Tampa, FL

Job posting number: #7141786 (Ref:hlj_44561)

Posted: April 24, 2023

Application Deadline: Open Until Filled

Job Description

Dr. Patrick Hwu’s lab at the Moffitt Cancer Center in Tampa, Florida is seeking a highly motivated Postdoc to join his multi-disciplinary laboratory team focused on understanding the underlying mechanisms of cancer-immune system interactions and developing novel translational cellular immunotherapies with the goal to improve current treatments for cancer patients.

Dr. Hwu’s research is engaged in developing innovative immunotherapy approaches to trigger potent adaptive antitumor immunity to overcome resistance to cancer immunotherapy. His studies are focused on gene-modified T-cells, development of translational combinatorial therapies which include immune checkpoint blockade and adoptive T-cell therapy, and identification of targetable T-cell molecules to boost the proliferation, migration and function of tumor reactive T-cells.

Position Highlights:
The candidate will be given the opportunities for developing new skills, professional growth, and career goals.
The candidate will receive outstanding mentorship from expert faculty and participate in multiple academic activities.

The Ideal Candidate:
Must have extensive practical experience with in vitro and in vivo techniques in a research lab setting.
Experience in biomedical engineering, assay development, molecular biology techniques, and gene editing methodologies, including CRISPR technology is strongly preferred.
Experience working with adoptive T-cell therapies, chimeric antigen receptor (CART-T) and/or transgenic T-cell receptor (TCR) development is strongly preferred.

The candidate is expected to:
Execute genetic in vivo and in vitro CRISPR screen with our team.
Develop chimeric antigen receptors for T-cell therapy in a mentored role.
Work reliably with a team to execute projects, complete routine laboratory duties, and maintain excellent records.
Design experiments, develop independent projects, and draft manuscripts.
Mentor undergraduate and PhD students as well as Postdocs, as appropriate.
Collaborate professionally and collegially with others in the lab and with other laboratories from diverse backgrounds and cultures.
Be enthusiastic about their role in improving the lives of cancer patients.
Be well-organized and detail-oriented, with the ability to effectively and reliably document protocols and experiments in ways that can be understood and replicated by others.

Credentials and Qualifications:
Must have completed an MD or PhD in biomedical engineering, biomedical sciences, immunology, or similar field with 3 years or more prior postdoctoral experience.

How to apply:
Please be sure to attach a single PDF file that includes a cover letter summarizing your previous research experience and accomplishments. A personal statement of scientific interests and goals, current CV with recent publications, and contact information for three references for Dr. Patrick Hwu to review. Questions regarding the position can be sent to the lab manager Ana Dominguez at [email protected].

Moffitt Postdocs are provided with Medical (Moffitt covers premium for team member) effective upon start date and eligible for Dental, Vision, Paid Time Off, Retirement, Parental Leave and more. You may be eligible for relocation assistance per policy. Reason to relocate, Tampa is a thriving metropolitan city that provides its residents a high quality of life.  The Tampa Bay area has become a hub for ground-breaking research, welcoming individuals from around the globe. This diverse city is engulfed with rich culture, year-round activities for all, beautiful beaches, amazing cuisine and so much more. 


If you have the vision, passion, and dedication to contribute to our mission,

then we have a place for you.

Mission To create a Moffitt culture of diversity, equity, and inclusion as we strive to contribute to the prevention and cure of cancer. Vision To advance and accelerate a culture of access, equity, and inclusion. Diversity is a priority at Moffitt and is meant "to promote a culture of diversity and inclusion as we contribute to the prevention and cure of cancer." The Enterprise Equity Department focuses its efforts on eliminating those obstacles to an individual’s ability to exist within their personal comfort zone at the cancer center. Everyone is important to meeting this priority. Addressing and responding to diversity and inclusion fosters an environment where mutual respect for diverse cultures, communication styles, languages, customs, beliefs, values, traditions, experiences and other ways in which we identify ourselves, is the expectation.

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