Baylor College of Medicine
Job posting number: #7123733 (Ref:14691-en_US)
Posted: February 9, 2023
Application Deadline: Open Until Filled
A postdoc position is available at Baylor College of Medicine in Houston. We are looking for a highly motivated candidate interested in studying how the microbiome contributes to intestinal inflammation and systemic disorders (such as the brain) using sophisticated mouse models and mouse/human intestinal organoids. The goal of this NIH-funded project is to identify the underlying mechanisms through which short telomeres and the microbiome predispose patients to intestinal inflammation and disorders of the brain. The work will cover several exciting novel research areas including microbiome-intestinal and microbiome-brain interaction.
This position offers the opportunity to learn about the emerging field of the microbiome and its impact on human health and disease.
- Possesses the intellectual and organizational ability to work on the project alone and in a team.
- Performs animal and cell studies.
- Collects and organizes data.
- Carries out other lab-related work as needed.
- Acquires the theoretical and practical knowledge in the area of telomere, microbiome and brain disorders such as autism through reading and working with others.
- Plans and carries out mouse and cell studies, including analysis of tissues and mouse and human organoids.
- Carry out mouse studies, including:
- analyzing tissues at the RNA (single cell RNAseq, RT-qPCR),
- protein (IHC, western blot, proteomics) and structural (electron and scanning microscopy) level.
- Carry out mouse studies, including:
- Generates intestinal organoids from mice and patients and performs studies to understand the impact of telomere shortening and the microbiome on intestine and the brain.
- Performs microbial studies to understand how the microbiome affects brain disorders such as autism.
- MD or Ph.D. in Basic Science, Health Science, or a related field.
- No experience required.
- The qualifications that are required are a PhD or MD with sufficient experience in basic science.
- The ideal candidate would be familiar with intestinal organoid work and mouse models.
- Knowledge of microbiology and microbiome would be advatageous.
- Motivated candidates without prior experience in these areas, but strong motivation to learn will be considered.
- Knowledge of common molecular techniques is required.
- A proof of excellence through publications in peer-reviewed journals is important.
- The candidate should be proficient in spoken and written English.
- The ideal candidate should be curious, self-motivated, and interested in working with others.
- This position will provide a supportive and highly innovative scientific environment and offer excellent opportinuties to contribute to several important biomedical areas.
Baylor College of Medicine requires employees to be fully vaccinated -subject to approved exemptions-against vaccine-preventable diseases including, but not limited to, COVID-19 and influenza.
Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.
PD; CA; CH; SN
Baylor College of Medicine fosters diversity among its students, trainees, faculty and staff as a prerequisite to accomplishing our institutional mission, and setting standards for excellence in training healthcare providers and biomedical scientists, promoting scientific innovation, and providing patient-centered care. - Diversity, respect, and inclusiveness create an environment that is conducive to academic excellence, and strengthens our institution by increasing talent, encouraging creativity, and ensuring a broader perspective. - Diversity helps position Baylor to reduce disparities in health and healthcare access and to better address the needs of the community we serve. - Baylor is committed to recruiting and retaining outstanding students, trainees, faculty and staff from diverse backgrounds by providing a welcoming, supportive learning environment for all members of the Baylor community.