Postdoctoral Fellow - Drug Development and Discovery

City of Hope

Monrovia, CA

Job posting number: #7110521 (Ref:10017841)

Posted: September 14, 2022

Application Deadline: Open Until Filled

Job Description

About City of Hope

City of Hope is an independent biomedical research and treatment organization for cancer, diabetes, and other life-threatening diseases.

Founded in 1913, City of Hope is a leader in bone marrow transplantation and immunotherapy such as CAR T cell therapy. City of Hope’s translational research and personalized treatment protocols advance care throughout the world. Human synthetic insulin, monoclonal antibodies and numerous breakthrough cancer drugs are based on technology developed at the institution.  AccessHope™, a subsidiary launched in 2019 serves employers and their health care partners by providing access to City of Hope’s specialized cancer expertise.

A National Cancer Institute-designated comprehensive cancer center and a founding member of the National Comprehensive Cancer Network, City of Hope is ranked among the nation’s “Best Hospitals” in cancer by U.S. News & World Report and received Magnet Recognition from the American Nurses Credentialing Center. Its main campus is located near Los Angeles, with additional locations throughout Southern California and in Arizona.

City of Hope’s commitment to Diversity, Equity, and Inclusion

We believe diversity, equity and inclusion is key in serving our mission to provide compassionate patient care, drive innovative discovery, and advance vital education focused on eliminating cancer and diabetes in all our communities.  Our commitment to Diversity, Equity and Inclusion ensures we bring the full range of skills, perspectives, cultural backgrounds, and experiences to our work -- and that our teams align with the people we serve to build trust and understanding.  We are dedicated to fostering a community that embraces diversity - in ideas, backgrounds, and perspectives; this is reflected in our work and represented in our people.

Position Summary

A Postdoctoral Fellow position is available in the laboratory of Dr. Guido Marcucci, M.D., Chair and Professor, Department of Hematologic Malignancies Translational Science, Director, Gehr Family Center for Leukemia Research, Chief, Division of Leukemia.


The Postdoctoral research fellow will work on our funded multi-projects.  The postdoc will explore signaling pathways relevant to drug development and discovery of basic mechanisms of leukemogenesis and novel therapeutic targets and epigenetic and genetic prognostic biomarkers in hematologic malignancies.  The postdoc will be responsible for design and perform in vitro and in vivo experiment, data collection and analysis, grant writing, publications, dissemination, and the overall day-to-day running of the project.

Applicants must possess a relevant PhD in Cancer Biology or Molecular Biology or a related field of study.  The applicant should have experience of conducting research, publishing journal papers, presenting research at conferences, and advanced quantitative data analyses.  The successful applicant should also be able to work collaboratively, supervise the works of others and act as a team leader as required.  In vivo experience including working with mouse models, transplantation, injection (IP, IV, oral gavage, retro orbital) and flow cytometry analysis is a plus. 

Basic education, experience and skills required for consideration:

  • Ph.D. in degree in life or biomedical sciences or a related discipline is required.

Additional Information:

As a condition of employment, City of Hope requires staff to comply with all state and federal vaccination mandates.

  • For more information on Dr. Guido Marcucci’s lab please visit here.

City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer.  All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.


City of Hope is a community of people characterized by our diversity of thought, background and approach, but tied together by our commitment to care for and cure those with cancer and other life-threatening diseases. The innovation that our diversity produces in the areas of research, treatment, philanthropy and education has made us national leaders in this fight. Our unique and diverse workforce provides us the ability to understand our patients' needs, deliver compassionate care and continue the quest for a cure for life-threatening diseases. At City of Hope, diversity and inclusion is a core value at the heart of our mission. We strive to create an inclusive workplace environment that engages all of our employees and provides them with opportunities to develop and grow, both personally and professionally. Each day brings an opportunity to strengthen our work, leverage our different perspectives and improve our patients’ experiences by learning from others. Diversity and inclusion is about much more than policies and campaigns. It is an integral part of who we are as an institution, how we operate and how we see our future.

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