Postdoctoral Associate- Large Scale Biophysical Modeling of Neurons

Baylor College of Medicine

Houston, TX

Job posting number: #7109567 (Ref:12967-en_US)

Posted: September 2, 2022

Application Deadline: Open Until Filled

Job Description


The goal of this project is to apply methods derived from large-scale optimization and optimal control towards the optimization of neuron models having a large number of electrical compartments. The developed techniques will be used to fit in vivo and in vitro electrophysiological data from murine CA1 pyramidal cells to understand the formation of their associated place fields. In addition, the same techniques will be applied to fit electrophysiological data from a visual neuron that detects impending collision in grasshoppers.

Job Duties

  • Develops methods to efficiently optimize large-scale compartmental neuron models.
  • Implements these methods through computer programing and test their efficiency using experimental data gathered in two model systems:
    • murine CA1 pyramidal cells
    • collision detection neurons in grasshoppers.

Minimum Qualifications

  • MD or Ph.D. in Basic Science, Health Science, or a related field.
  • No experience required.

Preferred Qualifications

  • Familiar with systems of ordinary differential equations of Hodgkin-Huxley type used to model neurons.
  • Experience in computer programing which will be central to the project’s execution.
  • Ph.D. in Computational Neuroscience, or a related field such as Electrical Engineering, Computer Science, Biophysics or Applied Mathematics.



Baylor College of Medicine requires employees to be fully vaccinated -subject to approved exemptions-against vaccine-preventable diseases including, but not limited to, COVID-19 and influenza.


Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.



Baylor College of Medicine fosters diversity among its students, trainees, faculty and staff as a prerequisite to accomplishing our institutional mission, and setting standards for excellence in training healthcare providers and biomedical scientists, promoting scientific innovation, and providing patient-centered care. - Diversity, respect, and inclusiveness create an environment that is conducive to academic excellence, and strengthens our institution by increasing talent, encouraging creativity, and ensuring a broader perspective. - Diversity helps position Baylor to reduce disparities in health and healthcare access and to better address the needs of the community we serve. - Baylor is committed to recruiting and retaining outstanding students, trainees, faculty and staff from diverse backgrounds by providing a welcoming, supportive learning environment for all members of the Baylor community.

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Job posting number:#7109567 (Ref:12967-en_US)
Application Deadline:Open Until Filled
Employer Location:Baylor College of Medicine
United States
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