Bioinformatics Associate Director, Molecular Pathology and Cytogenomics – Bioinformatics Professional Staff at Cleveland Clinic

Cleveland Clinic

Cleveland, OH

Job posting number: #7100709 (Ref:ccf15839139)

Posted: May 19, 2022

Application Deadline: Open Until Filled

Job Description

Bioinformatics Associate Director, Molecular Pathology and Cytogenomics – Bioinformatics Professional Staff

The Department of Laboratory Medicine at the Cleveland Clinic is currently seeking an Associate Director of Bioinformatics within the Molecular Pathology and Cytogenomics Section. We are seeking a PhD or MD/PhD with expertise in bioinformatics and genomics to support our growing Section's clinical and research needs. The position is a full-time clinical Professional Staff appointment; academic appointment through the Cleveland Clinic Lerner College of Medicine is available and encouraged. Working closely with the Bioinformatics Director, the Section Head and medical directors, the successful candidate will work collaboratively to support the development and maintenance of the data analytic and bioinformatics and reporting infrastructure, required to support our continued expansion of next generation sequencing and other high complexity assays within molecular genetics, oncology and hematopathology.

The successful candidate will spend the majority of their effort in clinical endeavors. Clinical responsibilities can include development and maintenance of bioinformatics pipelines and complex workflows (alignment, variant calling, variant annotation, copy number analysis, gene fusion, etc.), validation and documentation of bioinformatics pipelines, algorithms and tools in compliance with clinical accreditation requirements (i.e., CAP), development and implementation of applications to support variant annotation and report generation to streamline clinical data review and reporting, and integration of various data resources to support clinical workflows. The candidate would be expected to support the bioinformatics component of the clinical NGS workflow, provide technical expertise to assist in clinical review of assay quality metrics, results and other workflow troubleshooting, provide bioinformatics data analyses, summaries and visualizations for quality management, as well as work in collaboration with institutional IT and computing personnel to maintain NGS server hardware and software.

Although the majority of the candidate's efforts will be in clinical operations, participation in activities that support Cleveland Clinic's educational and research mission is encouraged and expected. There are multiple opportunities for research within clinical and anatomic pathology, including new efforts in Pathology AI, as well as across other clinical disciplines. Further research opportunities exist in projects involving data mining, analysis, and visualization of large-scale integrated data sets from genomic and clinical sources.

Candidates must have a PhD in Computational Biology, Biomedical Informatics, Data Science, Bioinformatics, Genomics, or a closely related discipline. It is strongly preferred that candidates have a minimum of one year of post-doctoral research or equivalent experience in an academic or clinical setting. Preference will be given to candidates with previous experience building bioinformatics algorithms and pipelines for processing genomic data, database development, and those who have worked in a CAP/CLIA accredited clinical laboratory setting. Broad experience in computational bioinformatics including Perl/Python programming, experience in Linux/Unix working environments, shell scripting, SQL (Structure Query Language), web-application development, as well as familiarity with various open source and commercial bioinformatics resources/software for NGS data analysis and variant annotation is desired. Ideally, the candidate will have experience using HPC or similar resources for high throughput computing. The candidate should demonstrate excellent communication and collaboration skills.

A faculty appointment at a rank commensurate with experience is available at Cleveland Clinic Lerner College of Medicine at Case Western Reserve University.

For more information, contact Elizabeth Azzato, MD, PhD, Section Head of Molecular Pathology and Cytogenomics Staff

([email protected], 216-444-8116)

About Us

Cleveland Clinic's vision is to become the best place for care and the best place to work in healthcare. We are committed to providing a safe, stable, and financially fulfilling work environment.  Even in these uncertain times, Cleveland Clinic is ambitiously investing in growth. Being a physician-led organization means doing what is best for the patients, every day.

Cleveland Clinic is one of the world's largest and busiest health centers.Patients come to Cleveland Clinic from all over the world. We offer advanced treatment for all illnesses and disorders of the body. We enjoy a strong reputation for outstanding quality care. U.S News & World Report Hospitals ranking of 2021-2022 has named us the No. 2 hospital in the nation once again and No.1 hospital for Ohio and metro areas for Cleveland, Akron and Miami/Ft. Lauderdale. Cleveland Clinic's heart program has ranked No. 1 in the nation since 1995. 

We are ranked nationally in 13 specialties, including 11 in the Top 10 and eight in the Top 5.

Other specialties noted for national excellence include ENT and pediatrics. Cleveland Clinic Children's offers highly specialized pediatric care in a family-centered atmosphere. It has been ranked the best children's hospital in Ohio by Child magazine.

In addition, Cleveland Clinic has been recognized as the No. 2 hospital in the world by Newsweek's World's Best Hospitals 2021 list.

Cleveland Clinic main campus and Cleveland Clinic Fairview Hospital are ranked internationally while five other locations are listed among the best hospitals nationwide -

  • Cleveland Clinic Akron General Hospital
  • Cleveland Clinic Avon Hospital
  • Cleveland Clinic Florida-Weston
  • Cleveland Clinic Hillcrest Hospital
  • Cleveland Clinic Lutheran Hospital

Cleveland Clinic was founded in 1921 as a not-for-profit group practice, integrating clinical and hospital care with research and physician education. In addition to our Cleveland location, we have Cleveland Clinic Florida, Cleveland Clinic Nevada, Cleveland Clinic Canada, Cleveland Clinic Abu Dhabi and Cleveland Clinic London. Take a tour of our main campus!

Cleveland Clinic has more than 4,200 salaried physicians and scientists on staff, representing approximately 120 specialties and subspecialties. Patients came to us from across America and from more than 180 nations. We also lead an extensive system of community hospitals in Northeast Ohio called the Cleveland Clinic Hospitals.

This system is made up of Cleveland Clinic Main Campus, Akron General Hospital, Avon Hospital, Euclid Hospital, Fairview Hospital, Hillcrest Hospital, Lodi Hospital, Lutheran Hospital, Marymount Hospital, Medina Hospital, Mercy Hospital, South Pointe Hospital, and Union Hospital. Ashtabula County Medical Center is also an affiliate of Cleveland Clinic. With approximately 5,895 staffed beds, Cleveland Clinic Hospitals offers broad geographic coverage, a full continuum of care, improved quality and lower cost of care to Northeast Ohio residents.

Cleveland Clinic was named a top hospital and health system by Diversity Inc. in 2020. Companies on this list score well in talent pipeline, talent development, leadership commitment, and supplier diversity.



Our Culture

Cleveland Clinic values a culture where caregivers integrate diversity and inclusion throughout the enterprise. We respect and appreciate our similarities and differences; they enable us to better serve our patients, one another, and our global communities.

Cleveland Clinic is pleased to be an equal employment/affirmative action employer: Women/Minorities/Veterans/Individuals with Disabilities.

Smoke/drug free environment.

Any application submitted without a CV will delay the review process

Please be advised that all information entered in your application will only be shared with Cleveland Clinic and will not be distributed to third parties.

About the Community

Cleveland is part of Northeast Ohio which is composed of six metropolitan areas. Each of them provides affordable real estate, excellent schools, safe communities as well as an abundance of outdoor activities. Find out here how great it is to live in Cleveland!

Information for Candidates

Candidates will only be asked to provide personal documents once an offer of employment has been made and accepted. Recruitment scams are becoming increasingly common online, with false advertisements and requests for payment or personal details claiming to come from reputable organizations. Please be assured that our physician recruiters will never ask for payment from candidates at any stage of the recruitment or offer process.


Cleveland Clinic Health System administers an influenza prevention program as well as a COVID-19 vaccine program. You will be required to comply with both programs, which will include obtaining an influenza vaccination, COVID-19 vaccination, or an exemption.

By embracing and understanding the diversity EVERY ONE brings, Cleveland Clinic has created an inclusive culture that promotes innovation, growth, and new ideas. This has enhanced our ability to attract the best global talent to provide the best patient experience possible. Cleveland Clinic is pleased to be an equal employment/affirmative action employer: Women/Minorities/Veterans/Individuals with Disabilities. Smoke/drug free environment.

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Job posting number:#7100709 (Ref:ccf15839139)
Application Deadline:Open Until Filled
Employer Location:Cleveland Clinic
United States
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