Associate Research Scientist | Cell & Molecular Biology | Hinson Lab
Job posting number: #7097773 (Ref:JR001756)
Posted: April 8, 2022
Application Deadline: Open Until Filled
Associate Research Scientist | Cell and Molecular Biology
The Hinson lab is seeking an independent, highly motivated PhD-level scientist to lead our NIH-funded genome-editing program with an overarching goal to develop genome editing therapeutics such as CRISPR for inherited cardiovascular disorders.
The ideal candidate would have a strong training background in cell and molecular biology, and prior expertise in mouse physiology particularly for cardiometabolic disorders would be highly desirable. Through leading this program, this talented individual would have access to a world-class consortium of experts in genome editing, delivery systems, and microphysiological human tissue and organoid models.
The Hinson lab at the Jackson Laboratory for Genomic Medicine and UConn Health studies human cardiovascular disorders especially heart failure using a combination of approaches including genome editing, pluripotent stem cell technology, genomics assays, and tissue engineering.
- Ph.D. in cell biology, molecular biology, genetics, or related field of study.
- 3+ years of post-doctoral training is desirable
- Prior research experience in at least two of the following areas: pluripotent stem cell biology and cardiomyocyte differentiation, CRISPR/TALEN or related genome editors, viral vector design and production, mouse/rodent physiology, and next-generation genome sequencing assays.
- Experience in single cell technologies for transcriptomics; flow cytometry (or other forms of cytometric analyses); cellular histology and confocal microscopy especially live-cell imaging; and AAV design, production and in vivo animal validation are particularly desirable skills.
- Experience with R, Python or similar statistical package is helpful, as well as experience with clustering, pathway, genetic and genomic data analyses and bioinformatics.
- Candidates should have a publication record in peer-reviewed journals.
- Excellent writing and communication skills, able to work independently and effectively with other members in a productive team.
**Please submit your current CV and 1-page (maximum) statement of Research Interests and Career Goals at time of application. **
We are a diverse and inclusive research group, aspiring to produce top science and scientists through attentive and progressive mentoring and interdisciplinary teamwork.
The Jackson Laboratory (JAX) is an independent, nonprofit biomedical research institution with more than 2,400 employees. Headquartered in Bar Harbor, Maine, it has a National Cancer Institute-designated Cancer Center in Augusta, Maine, a genomic medicine institute in Farmington, Connecticut, and facilities in Ellsworth, Maine, Sacramento, California, and Shanghai, China. Its mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health.
JAX employees work in a collaborative, value-driven, and team-based environment where the focus is on advancing science and improving patients’ lives. Researchers apply genetics to increase the understanding of human disease and advance treatments and cures for cancer, neurological and immune disorders, diabetes, aging, and heart disease. JAX was voted among the top 15 “Best Places to Work in Academia” in the United States in a poll conducted by The Scientist magazine!
The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.