Postdoctoral fellowship on epigenetic regulation and the DNA Damage response in normal and malignant hematopoiesis

The University of Texas M. D. Anderson Cancer Center

Houston, TX

Job posting number: #7096623

Posted: March 29, 2022

Application Deadline: Open Until Filled

Job Description

A post-doctoral fellowship in Cancer Biology and Epigenetics is immediately available in the lab of Dr. Margarida Santos at MD Anderson Cancer Center. The research will focus on the intersection of epigenetics and the DNA Damage Response (DDR) in cancer initiation, progression and targeting. The long-term goal is to understand the mechanisms through which Epigenetic regulation and its interplay with the DDR occurs during normal differentiation and how these processes become disrupted in human diseases and use this information to develop specific and potent therapeutic strategies.

Training and research activities will include work with genetic mouse models of Acute Myeloid Leukemia and Diffuse Large B Cell Lymphoma, as well as human cell lines and patient derived samples. Next Generation Sequencing, such as RNA-seq and ChIP-seq, and CRISPR screens will be performed among other molecular biology techniques. Fluorescent/confocal microscopy and flow cytometry are also components of the research program.

Dr. Santos’ laboratory has received numerous prestigious awards and strong funding support. For more information, please visit

Candidate must be a recent Ph.D. or MD/Ph.D. graduate in biochemistry, genetics, immunology, cancer biology, or similar field. An excellent publication record (only candidates with one or more first-authored publications in a high impact journal(s) will be considered), along with experience in generating/characterizing mouse models, flow cytometry, viral transduction, mammalian cell culture and next generation sequencing is required. Previous experience in scientific writing or grant preparation in English is required. Please apply via link below with your CV, Publication(s), and Statement of Research Experience and Interest.

It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law.

Apply Now

Please mention to the employer that you saw this ad on

Job posting number:#7096623
Application Deadline:Open Until Filled
Employer Location:The University of Texas MD Anderson Cancer Center
United States
More jobs from this employer
Institution Website, an AmeriCareers ® service.