About City of Hope

City of Hope is an independent biomedical research and treatment organization for cancer, diabetes and other life-threatening diseases.

Founded in 1913, City of Hope is a leader in bone marrow transplantation and immunotherapy such as CAR T cell therapy. City of Hope’s translational research and personalized treatment protocols advance care throughout the world. Human synthetic insulin, monoclonal antibodies and numerous breakthrough cancer drugs are based on technology developed at the institution.  AccessHope™, a subsidiary launched in 2019 serves employers and their health care partners by providing access to City of Hope’s specialized cancer expertise.

A National Cancer Institute-designated comprehensive cancer center and a founding member of the National Comprehensive Cancer Network, City of Hope is ranked among the nation’s “Best Hospitals” in cancer by U.S. News & World Report and received Magnet Recognition from the American Nurses Credentialing Center. Its main campus is located near Los Angeles, with additional locations throughout Southern California and in Arizona.

City of Hope’s commitment to Diversity, Equity and Inclusion

We believe diversity, equity and inclusion is key in serving our mission to provide compassionate patient care, drive innovative discovery, and advance vital education focused on eliminating cancer and diabetes in all of our communities.  Our commitment to Diversity, Equity and Inclusion ensures we bring the full range of skills, perspectives, cultural backgrounds and experiences to our work -- and that our teams align with the people we serve in order to build trust and understanding.  We are dedicated to fostering a community that embraces diversity - in ideas, backgrounds and perspectives; this is reflected in our work and represented in our people.

City of Hope has one of the most influential type 1 and type 2 diabetes research programs in the world. Our scientists’ work has revolutionized the understanding and treatment of the disease and continues today with exciting developments in cell transplantation, gene regulation, immune tolerance and gaining systemic understanding of diabetes as a complex, multifaceted disease.

To learn more about our exciting research and accomplishments in the field of Diabetes, please visit https://www.cityofhope.org/research/riggs-institute.

Position Summary

The Beckman Research Institute of City of Hope is looking for a talented Postdoctoral Fellow within the laboratory of Debbie Thurmond, Ph.D. to study the molecular mechanisms involved in regulating functional beta cell mass, skeletal muscle insulin action, whole body glucose homeostasis, and healthspan/lifespan.

The Thurmond Lab specializes in detailed studies of signaling/trafficking/exocytosis, using primary human and rodent islet cells, skeletal muscle cells and adipocytes.

The position will encompass a variety of techniques, including human islet functional and structural characterizations in vitro and in vivo, biosensors and live-cell imaging, analysis of protein-protein interactions, CRISPR/small interference RNA, post-translational modifications such as phosphorylation/glycosylation/nitrosylation, as well as use of a variety of inducible tissue-specific transgenic and knockout animal models. The trainee will benefit from a close interaction with world-class clinical and basic science faculty and staff, and gain experience in state-of-the-art genomics, molecular genetics, cell biology, and animal model manipulations.

Basic education, experience and skills required for consideration:

A Ph.D. degree in life or biomedical sciences, or a related discipline is required.

Additional Information:

About Dr. Thurmond: Debbie Thurmond, Ph.D., is director of the Arthur Riggs Diabetes & Metabolism Research Institute and a renowned research scientist, professor and the founding chair of the newly created Department of Molecular and Cellular Endocrinology.

Dr. Thurmond and her team will lead efforts to identify cellular and molecular mechanisms in diabetes development and therapies that can stop or reverse those processes. This can potentially lead to innovative treatment and prevention modalities for diabetes.

For more information about the Thurmond Lab, please click here.

As a condition of employment, City of Hope requires staff to comply with all state and federal vaccination mandates.

City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer.  All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.

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