Postdoctoral Research Associate, Wambre Lab

Benaroya Research Institute

Seattle, WA

Job posting number: #7087400

Posted: October 19, 2021

Application Deadline: Open Until Filled

Job Description

Benaroya Research Institute at Virginia Mason (BRI) has a bold mission: Predict, prevent, reverse and cure immune system diseases, from autoimmune disease to cancer to COVID-19. We examine the immune system in both health and disease to understand how disorders start and how to rebalance the immune system back to health. Equipped with innovative tools and robust biorepositories, our team chips away at the biggest mysteries behind these conditions to work toward our vision of a healthy immune system for all. As an independent non-profit organization within Virginia Mason Franciscan Health, we collaborate with clinicians to accelerate the path from innovative lab discoveries to life-changing patient care.

At BRI, each role is valued and an important contributor to the vision and mission. BRI is committed to a safe, caring and diverse workplace; as well as to taking action to further our commitments to foster inclusion, equity and belonging so employees feel comfortable bringing their full selves to work. Consider making a difference, join our team. Because together, we are Powering Possibility.

Visit BenaroyaResearch.org or follow BRI’s Autoimmune Life Blog, Facebook, Instagram, LinkedIn or Twitter to learn more.

Overview: The Wambre Lab at the Benaroya Research Institute (BRI) in Seattle, WA is seeking a Postdoctoral Research Associate who will be involved in research involving application of cutting edge cellular and molecular profiling techniques to current immunological problems in human health. Studies will focus on human antigen-specific CD4+ T cell responses including biomarker discovery in health and disease.

Responsibilities:
• Conceptualize and execute experiments, data analysis, laboratory record keeping, oral and written presentation of experimental results. The position may involve oversight/ supervision of technicians or graduate students.
• Lead experiments to characterize the cellular and molecular changes on human antigen-specific CD4+ T cells during current clinical trails within the context of the development of new immunotherapy and biomarkers for application in allergy, autoimmunity, infectious diseases and oncology
• Carry out bench work experiments, including single cell transcript analysis, and be responsible for checking and validating the results in each filed of activity
• Implement adequate experimental protocols and, if necessary, the experiments required to solve the possible technical problems within study deadlines
• Present results or summary of results to the project team or to other audiences as needed
• Write required documents such as experimental procedures, research articles and study reports
• Provide oversight/supervision of technicians or graduate students within the context of these studies

Requirements:
• Recent or anticipated PhD, MD or MD/PhD scientific discipline (Cell Biology, Immunology, or equivalent).
• Knowledge in cellular immunology with less than 4 years of postdoctoral experience
• Previous experience with T cell immunology, RNAseq, or knowledge in bioinformatics is a plus
• Significant experience in multi-parameter flow cytometry, and in design/set up of cell based assays
• Additional expertise in other laboratory techniques related to molecular biology and biochemistry research will also be considered
• Excellent verbal and written communication skills with good organizational and analytical abilities


All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, citizenship, disability or protected veteran status.




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