Postdoctoral Associate - Antibiotic Resistance Enzymology - Pharmacology & Chemical Biology - Palzkill

Baylor College of Medicine

Houston, TX

Job posting number: #7081571 (Ref:7967-en_US)

Posted: July 23, 2021

Application Deadline: Open Until Filled

Job Description

Job Purpose

Postdoctoral Associates are trainees working in an apprenticeship mode in preparation for a career as a scientific professional.

Job Duties

Postdoctoral Position in Antibiotic Resistance Enzyme Structure and Mechanism, Palzkill Lab

A postdoctoral associate position in mechanistic enzymology is available in the Department of Pharmacology and Chemical Biology at Baylor College of Medicine. The laboratory is interested in the structure and mechanism of antibiotic resistance enzymes. In particular, we are interested in the structural and mechanistic basis of action of naturally occurring, drug-resistant variants of beta-lactamase enzymes that result in the inactivation of beta-lactam antibiotics. These enzymes rapidly hydrolyze beta lactam antibiotics and are a major source of bacterial drug resistance. Knowledge gained on the structure and mechanism of these beta-lactamase variants will be used for rational drug design. The studies will involve protein purification, pre-steady state enzyme kinetic analysis and X-ray structure determination. The successful candidate will have experience in protein purification, enzymology, and X-ray crystallography.  Candidates should have a Ph.D. or M.D. degree and a strong record of productivity as evidenced by publications. Written and oral presentation skills as well as the ability to collaborate effectively are essential.

Minimum Qualifications

  • Education Required: MD or Ph.D. in Basic Science, Health Science, or a related field.
  • Experience Required: None Required.
  • Certification/Licenses/Registration: None Required.





Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.



Baylor College of Medicine fosters diversity among its students, trainees, faculty and staff as a prerequisite to accomplishing our institutional mission, and setting standards for excellence in training healthcare providers and biomedical scientists, promoting scientific innovation, and providing patient-centered care. - Diversity, respect, and inclusiveness create an environment that is conducive to academic excellence, and strengthens our institution by increasing talent, encouraging creativity, and ensuring a broader perspective. - Diversity helps position Baylor to reduce disparities in health and healthcare access and to better address the needs of the community we serve. - Baylor is committed to recruiting and retaining outstanding students, trainees, faculty and staff from diverse backgrounds by providing a welcoming, supportive learning environment for all members of the Baylor community.

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