Cancer Immunology Postdoctoral Fellow

H. Lee Moffitt Cancer Center

Tampa, FL

Job posting number: #7080184 (Ref:hlj_31416)

Posted: June 22, 2021

Application Deadline: Open Until Filled

Job Description

The laboratory of Dr. Dennis Adeegbe at the Moffitt Cancer Center Department of Immunology in Tampa, Florida seeks to recruit a Postdoctoral Fellow to contribute to immuno-oncology research efforts. 

The main focus of the lab is to understand the immunological and molecular landscape of solid tumor microenvironment with the goal of manipulating the immune component to promote anti-tumor immunity. In this regard, syngeneic, orthotopic and genetically engineered mouse models as well as patient specimens are employed in both basic and translational studies of melanoma, lung, and prostate cancers. The lab utilizes an array of cellular, molecular, biochemical, and genomic analytical techniques to interrogate pertinent questions in a number of in vitro and in vivo studies.

Position Highlights: 
•    Conduct independent and collaborative studies in an Immunology lab focusing on both basic and clinically-relevant translational studies.
•    Opportunity to be a part of a fast-paced lab and acquire additional experience in Immuno-Oncology by contributing to projects and studies related to understanding the cancer immune environment.
•    Be involved in exciting projects to understand Tumor microenvironment in solid cancers and studies exploring biological factors underlying cancer health disparity and novel immunotherapeutic strategies.
•    Participation at scientific meetings, membership in relevant scientific organizations, and applying for training grants will be encouraged and supported.

Ideal Candidate:
•    Will have solid experience working with lab animals and expertise in at least one of the following cellular biology techniques:
       o    Multi-parameter Flow Cytometry; sample staining and acquisition, knowledge of analytical software such as FlowJo is a plus.
       o    Mouse and human cell culture; both primary cells as well as cell lines.
       o    ELISpot or Luminex-based assays for cytokine/chemokine assessments.
       o    Immunofluorescent staining, imaging and fluorescent microscopy.

•    Strong experience in cell signaling and molecular biology techniques:
        o    Western blot, Co-IP
        o    Gene editing via shRNA/siRNA or CRISPR.
•    Familiarity with murine syngeneic and genetically engineered models of lung/skin cancers as well as allografts/xenografts is a plus.
•    Familiarity with genomic or epigenomic analytical platforms such as RNA-sequencing, ChIP-sequencing also a plus.

•    Perform investigational studies utilizing animal models and patient specimen to understand the tumor microenvironment.
•    Execute experiments independently and contribute to collaborative projects. Write manuscripts for publishing.
•    Train and supervise junior staff and participate in overall lab management.
•    Analyze and present data at local and national meetings.

Credentials and Qualifications: 
Ph.D. and/or M.D. in Immunology, Cellular/Molecular Biology, or related fields. Hands-on-experience in laboratory research and good computer skills are required. 

Tampa was named an “urban gem” and the “Best City in the Southeast” by Money magazine.  Aside from the sunshine, beaches, and year-round outdoor recreation associated with the Gulf Coast of Florida, Tampa is a thriving metropolitan city with unique cultural attractions, low cost of living, and a high quality of life.

A competitive salary and benefits package will be offered to the successful candidate. Interested applicants should send a single PDF file of their current CV with publications list, and contact information for three references. For further inquiries, please email

Mission To create a Moffitt culture of diversity and inclusion as we strive to contribute to the prevention and cure of cancer. Vision Moffitt Cancer Center is recognized as the model wherein the diversity of our employees and communities is valued and supported as essential components to contributing to the prevention and cure of cancer. The cancer center is an equal opportunity employer. It is the policy of the cancer center to prohibit unlawful discrimination and harassment of any type and to afford equal employment opportunities to workforce members and applicants, regardless of race, color, religion, sex, sexual orientation, gender identity or expression, national origin, age, marital status, disability, genetic information, veteran’s status or any other characteristic protected by federal, state or local law.

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