Job posting number: #7063542 (Ref:10005077)
Posted: February 15, 2020
Application Deadline: Open Until Filled
Job DescriptionAbout City of Hope
City of Hope, an innovative biomedical research, treatment and educational institution with over 6000 employees, is dedicated to the prevention and cure of cancer and other life-threatening diseases and guided by a compassionate, patient-centered philosophy.
Founded in 1913 and headquartered in Duarte, California, City of Hope is a remarkable non-profit institution, where compassion and advanced care go hand-in-hand with excellence in clinical and scientific research. City of Hope is a National Cancer Institute designated Comprehensive Cancer Center and a founding member of the National Comprehensive Cancer Network, an alliance of the nation’s leading cancer centers that develops and institutes standards of care for cancer treatment.
NIH-funded postdoctoral research positions are available in the laboratory of Qiong (Annabel) Wang, in the Department of Molecular and Cellular Endocrinology at the City of Hope Beckman Research Institute. The Wang laboratory utilizes the cutting-edge tissue-specific, inducible knockout and lineage tracing mouse models to study the region-specific remodeling of fat tissue, both in physiological and pathological conditions, such as insulin resistance, obesity, and cancer.
Dr. Wang has previously generated the AdipoChaser mice model and tracked adipogenesis during fat tissue development and remodeling (Wang QA, et al. Nature Medicine , 2013 ). Dr. Wang’s other previous research generated a series of inducible knockout mouse models and revealed the surprising diversity of transcriptional signals required at different stages of adipogenesis in vivo (Wang QA, et al. Nature Cell Biology , 2015 ). The Wang lab is currently working on three projects: 1) Brown fat cell heterogeneity, and how this heterogeneity remodels the thermogenic capacity of brown adipocytes in health and disease (Song A, et al. Journal of Clinical Investigation , 2020 ) . 2) Fat tissue remodeling in the mammary gland in health, metabolic disorders and breast cancer (Wang QA, Song A, et al. Cell Metabolism , 2018 ) . 3) Aging-associated adipogenesis and fat expansion.
We are seeking independent and highly motivated candidates interested in studying the cellular and metabolic mechanisms leading to obesity, diabetes, and cancer. Preferably with expertise in using mouse models to study metabolic diseases.
Basic education, experience and skills required for consideration:
- Ph.D. and/or M.D..
- Extensive experience with basic molecular biology skills.
- Experience in animal models.
- Experience with immunofluorescence staining and flow cytometry.
- Excellent written and verbal communication skills.
- Good problem-solving skills, ability to conduct independent research, ability to work effectively in a team.
- To apply, please attach your CV and a list of three references.
City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.
City of Hope is a community of people characterized by our diversity of thought, background and approach, but tied together by our commitment to care for and cure those with cancer and other life-threatening diseases. The innovation that our diversity produces in the areas of research, treatment, philanthropy and education has made us national leaders in this fight. Our unique and diverse workforce provides us the ability to understand our patients' needs, deliver compassionate care and continue the quest for a cure for life-threatening diseases. At City of Hope, diversity and inclusion is a core value at the heart of our mission. We strive to create an inclusive workplace environment that engages all of our employees and provides them with opportunities to develop and grow, both personally and professionally. Each day brings an opportunity to strengthen our work, leverage our different perspectives and improve our patients’ experiences by learning from others. Diversity and inclusion is about much more than policies and campaigns. It is an integral part of who we are as an institution, how we operate and how we see our future.