Postdoctoral Fellow - Stem Cell Biology

City of Hope

Duarte, CA

Job posting number: #7063534 (Ref:10005369)

Posted: February 15, 2020

Application Deadline: Open Until Filled

Job Description

About City of Hope
City of Hope, an innovative biomedical research, treatment and educational institution with over 6,000 employees, is dedicated to the prevention and cure of cancer and other life-threatening diseases and guided by a compassionate, patient-centered philosophy.

Founded in 1913 and headquartered in Duarte, California, City of Hope is a remarkable non-profit institution, where compassion and advanced care go hand-in-hand with excellence in clinical and scientific research. City of Hope is a National Cancer Institute designated Comprehensive Cancer Center and a founding member of the National Comprehensive Cancer Network, an alliance of the nation’s leading cancer centers that develops and institutes standards of care for cancer treatment.

Position Summary
The Beckman Research Institute of City of Hope is looking for a talented Postdoctoral Fellow.

Key Responsibilities include:
  • Design and perform independent experiments in tissue culture, and viral infections in rodent tumor models.
  • Design, rescue and characterize (in vitro) novel oncolytic viruses
  • Execute experiments especially BSL2 work in compliance with city of hope policies from set up to take down, and downstream cellular analysis.
  • Independently design and perform immune profiling experiments from preclinical and clinical samples.
  • Collect, analyze, and present scientific data to the team; with proposed next steps.
  • Self-motivated and driven to work independently and collaboratively as part of a team.
  • Coordinate research efforts and make key scientific and technical contributions for the strategic development of cross-functional projects.
  • The candidate will perform independent experimental research, but will work in close collaboration with the rest of the scientific team in a highly cross-functional and project-oriented environment.
  • Work closely and collaboratively with fellow employees


Qualifications
Basic education, experience and skills required for consideration:
  • A Ph.D. in Virology, Immunology, Molecular/Cellular Biology, Biochemistry, or a related field.
  • Industry or academic experience in virotherapy, immunology, in vivo oncology and or pharmacology.
  • Proficiency in cloning and virus engineering or have the background and skills to master them in a short period of time.
  • Proficiency in numerous mouse techniques, including various routes of injection, mouse tumor models, and murine immunology.
  • Track record of recent scientific publications
  • Ability to learn and acquire new methods and emerging technologies; must be able to adapt, develop, and validate published assays into the new lab environment.
  • Excellent organizational and time-management skills.
  • Ability to work independently and as part of a team.
  • Broad experience with immunological and molecular principles and techniques including primary cell isolation/culture, ELISA, cell sorting, qPCR, RT-PCR, RNA and DNA isolation
  • Cell proliferation and cytotoxicity assay
  • Virus rescue and amplification
  • Molecular cloning of viral vectors for gene therapy or oncolytics.
  • Team spirit and ability to work in a multidisciplinary matrix environment.
Preferred education, experience and skills:
  • In vivo oncology
  • Experience working with various mammalian cell lines
  • Molecular Cloning
  • Virotherapy
  • Immunology
  • Proteomics
  • ELISPOT
  • Flow cytometry
City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.



City of Hope is a community of people characterized by our diversity of thought, background and approach, but tied together by our commitment to care for and cure those with cancer and other life-threatening diseases. The innovation that our diversity produces in the areas of research, treatment, philanthropy and education has made us national leaders in this fight. Our unique and diverse workforce provides us the ability to understand our patients' needs, deliver compassionate care and continue the quest for a cure for life-threatening diseases. At City of Hope, diversity and inclusion is a core value at the heart of our mission. We strive to create an inclusive workplace environment that engages all of our employees and provides them with opportunities to develop and grow, both personally and professionally. Each day brings an opportunity to strengthen our work, leverage our different perspectives and improve our patients’ experiences by learning from others. Diversity and inclusion is about much more than policies and campaigns. It is an integral part of who we are as an institution, how we operate and how we see our future.


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