Dr. Yingbin Fu's laboratory at Baylor College of Medicine (BCM) is seeking a talented post-doctoral associate. The Fu lab is interested in using the visual system to study sensory transduction, the biological mechanisms underlying various types of neurodegeneration, and to develop innovative treatment strategies. Recently, the Fu lab has made significant progress toward the understanding of two blinding diseases: Leber congenital amaurosis (LCA), the most severe retinal dystrophy in early childhood, and age-related macular degeneration (AMD), the leading cause of irreversible blindness in the elderly. The PI has won the National Eye Institute Audacious Goals Challenge Prize (http://www.nei.nih.gov/challenge). The candidate is expected to develop a highly innovative and effective treatment for AMD by targeting its multiple underlying causes including cholesterol metabolism, angiogenesis, inflammation, etc. The lab uses the following techniques for this study: histopathology on animal models and human specimens, transcriptome profiling, advanced in vivo imaging in animal models, gene therapy, drug delivery, etc. Prior experience in these areas is preferred. The Fu lab is particularly interested in using the visual system to address post-genomic era challenges (e.g. translate enormous genetic information to functional information). We place emphasis in "Translational Research": from "discovering mechanisms" to "developing innovative treatment strategies" to "moving into clinical trials". Due to the translational nature of our research, students and postdocs will have good employment opportunities in both academia and industry.
Lab web site: https://www.bcm.edu/people/view/yingbin-fu-ph-d/1e992a12-03c2-11e5-8d53-005056b104b