Postdoctoral Scholar - Psychiatry

University of Pittsburgh

Pittsburgh, PA

Job posting number: #7111019 (Ref:pt1002)

Posted: September 18, 2022

Application Deadline: Open Until Filled

Job Description

The NIMH-funded IMPACT (Innovative Methods in Pathogenesis and Child Treatment) postdoctoral training program at Western Psychiatric Hospital (WPH) within the Department of Psychiatry and The University of Pittsburgh School of Medicine is seeking creative and energetic post-doctoral (MD or PhD) fellows in mental-health related disciplines.

The IMPACT two-year, NIMH funded training program matches creative and energetic post-doctoral (MD, PhD, DO, or MD, PhD) fellows in mental health-related disciplines with faculty members who provide mentorship across an array of approaches and methods, including fMRI, genetics, statistical modelling, treatment evaluation, and implementation science. In addition, we provide resources for travel, coursework, and pilot research.
The program, which has been funded continuously since 1990, aims to develop clinical scientists who can formulate original and significant research in areas such as:

• Mechanisms of pathogenesis, persistence and treatment response
• Translation of basic research findings into clinical interventions
• Identification of individual differences in treatment response that leads to
personalization and optimization of treatment
• Implementation of effective interventions in community settings
• Strategies for the dissemination of effective treatments; and
• Consumer, provider, and contextual determinants of intervention
acceptability, effectiveness, and uptake.

Fellows at Western Psychiatric Hospital at the University of Pittsburgh School of Medicine have an opportunity to work with respected, multi-disciplinary faculty in one of the strongest child and adolescent psychiatry clinical and research program in the United States.

Representative ongoing faculty mentor funded projects include:
1. Assessment and Management of Depressed and Suicidal Youth in Pediatric Primary Care (ETUDES): A multidisciplinary Center aiming to develop innovative, effective, sustainable interventions that improve the detection, triage, engagement, and management of depressed and suicidal youth in pediatric primary care utilizing a dissemination and implementation framework.
2. Prediction of Suicidality among Youth Presenting to a Psychiatric Emergency Department (EASY). Examination of the accuracy of adaptive testing, machine learning and natural language processing, and theory-driven suicide risk assessment to predict suicidal behavior in youth presenting to a psychiatric emergency department.
3. Early Intervention for Youth At-Risk for Bipolar Disorder (KEY): A randomized controlled confirmatory efficacy trial to examine Interpersonal and Social Rhythm Therapy (IPSRT) as compared with a control treatment delivered via telehealth aiming to prevent or ameliorate the progression of bipolar disorder in high-risk adolescents (adolescent offspring of parents with bipolar disorder). Novel methods include objective assessment of sleep/wake via actigraphy, mobile sensing via smartphone app to assess activity, and application of a clinical tool (risk calculator) that reliably predicts risk for bipolar onset to both identify participants and examine treatment response.
4. Longitudinal Phenotyping of Bipolar Disorder (BD-LONG): A longitudinal neuroimaging study that aims to identify person-level markers of the “mood switch” in bipolar disorder, by scanning affected individuals in different mood states over the course of 9 months and correlating with passive smartphone data and clinical assessments.
5. Inflammation and Stress Response in Familial and Nonfamilial Youth Suicidal Behavior (Fampath Study): To examine short-term or proximal biological risk profiles for suicidal behavior in stress response and inflammatory pathways, peripherally and in the brain, and examine familial and nonfamilial biological mechanisms for suicidal behavior in young adults.
6. Social-Affective Vulnerability to Suicidality among LGTBQ Young Adults: Proximal and Distal Factors. Rates of suicidal thoughts and behaviors (STB) among young adults have reached a crisis level, especially for those in the LGBTQ (i.e., lesbian, gay, bisexual, queer, questioning and/or transgender) population, who face social stigma in addition to the typical developmental challenges. Although we know the general risk factors for suicide, those have limited utility in predicting how, when, and in whom suicide occurs. It is critically important to consider the role of social context because STB often occurs in response to a recent social threat event such as rejection and could be more likely in those who have altered sensitivity of neural social circuitry.
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Job posting number:#7111019 (Ref:pt1002)
Application Deadline:Open Until Filled
Employer Location:University of Pittsburgh
United States
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